Search results for "Divinyl sulfone"

showing 3 items of 3 documents

ChemInform Abstract: Diels-Alder Reactions of in situ Generated N-Benzoylindolo-2,3- quinodimethane with Carbodienophiles.

2010

The indolo-2,3-quinodimethane (5), generated from 2,3-bis(bromomethyl)indole (4), was trapped with unsymmetrical carbodienophiles or N, N′-p-phenylenedimaleimide to furnish the 1,2,3,4-tetrahydrocarbazoles (6–9). [4 + 2]-Cycloaddition of 5 with tetracyanoethylene gave rise to the tetracyanocarbazole (10) and a subsequent product 11a or 11b. The Diels-Alder reaction of 5 with divinyl sulfone was regiospecific within the detection limits of HPLC analysis. Similarly, the reaction of 5 with N, N′-p-phenylenedimaleimide yielded solely the stereoisomer 9.

Detection limitIndole testIn situHplc analysischemistry.chemical_compoundchemistryDiels alderGeneral MedicineTetracyanoethyleneMedicinal chemistryDivinyl sulfoneChemInform
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Diels-Alder Reactions ofin situ generated N-benzoylindolo-2,3-quinodimethane with carbodienophiles

1993

The indolo-2,3-quinodimethane (5), generated from 2,3-bis(bromomethyl)indole (4), was trapped with unsymmetrical carbodienophiles or N, N′-p-phenylenedimaleimide to furnish the 1,2,3,4-tetrahydrocarbazoles (6–9). [4 + 2]-Cycloaddition of 5 with tetracyanoethylene gave rise to the tetracyanocarbazole (10) and a subsequent product 11a or 11b. The Diels-Alder reaction of 5 with divinyl sulfone was regiospecific within the detection limits of HPLC analysis. Similarly, the reaction of 5 with N, N′-p-phenylenedimaleimide yielded solely the stereoisomer 9.

Indole testIn situDetection limitHplc analysischemistry.chemical_compoundchemistryDiels alderOrganic chemistryTetracyanoethyleneDivinyl sulfoneJournal f�r Praktische Chemie/Chemiker-Zeitung
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Divinyl Sulfone Cross-Linked Hyperpolymeric Human Haemoglobin as an Artificial Oxygen Carrier in Anaesthetized Spontaneously Breathing Rats

1994

Hyperpolymeric haemoglobin in concentrations necessary to transport oxygen in organism to a significant extent exhibits a negligible oncotic pressure as compared to that of plasma. This property makes hyperpolymeric haemoglobins suitable for development of an artificial oxygen transporting blood additive. With such an additive - in contrast to an oxygen transporting plasma expander - combating a chronic oxygen deficit of tissue (brain, heart, kidney, extremities or in case of anaemia) is possible. Using in these cases an isoncotic oxygen carrying plasma expander instead of an additive would be even more detrimental because of fluid load to heart, at least in case of heart injury. Chronic ox…

Oncotic pressureKidneyHeart Injurymedicine.medical_specialtychemistry.chemical_elementOxygen deficitDivinyl sulfoneOxygenmedicine.anatomical_structureEndocrinologyBlood lossBiochemistrychemistryInternal medicinemedicineBreathing
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